Which of the following is NOT a common sign or symptom of Cushing syndrome?

In the context of Cushing syndrome, the correct response identifies weight loss as not being a common sign or symptom. Cushing syndrome is characterized by an excess of cortisol, which can lead to various physiological changes in the body. One of the hallmark features of this condition is weight gain, particularly in the trunk, face (often referred to as a "moon face"), and neck area, while the limbs may become thinner. This pattern of weight distribution occurs due to the body's altered metabolism resulting from high cortisol levels.

In contrast to weight loss, poor wound healing is indeed a prevalent symptom of Cushing syndrome. Elevated cortisol can impair the immune response and slow down the processes that are crucial for tissue repair, leading to prolonged healing times. Osteoporosis is also a well-documented complication as cortisol affects bone metabolism, inhibiting the formation of new bone and increasing the risk of fractures. Similarly, acne can manifest due to hormonal changes that accompany the excess cortisol, leading to increased oil production and clogged pores.

By recognizing that weight gain rather than loss is associated with Cushing syndrome, it becomes clear how significant the hormonal and metabolic changes are in this disorder. This understanding reinforces the distinction between Cushing syndrome and other conditions that may cause weight loss or different symptom